Development System
CM18-PTD4 | SCGE Toolkit
Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. |
CM18-PTD4 |
Calculated editing efficiency by T7E1 digestion. |
|
Editing Efficiency |
15000000534 |
|
AsCas12a (Feldan Therapeutics) |
CM18-PTD4 |
Amphiphilic peptide |
NKG2A |
|
|
Human |
NK |
|
|
|
1.33uM Cas12a/2.0uM gRNA/7.5uM Shuttle Peptide |
|
|
|
48 hours |
ribonucleoprotein (RNP) |
|
|
|
Measured Values |
Samples Size: | 3 |
|
Mean |
9.83  |
1 |
8.66051  |
2 |
8.90658  |
3 |
11.92783  |
| |
|
Publication Title |
Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. NCBI |