Experiment Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells. Experiment Condition CM18-PTD4, Cas9, CFTR Assay Description: Calculated editing efficiency mean of 3 biological replicates by sanger sequencing. Tissue Measured: Measurement Type: Editing Efficiency Record ID 15000000546 Editor SpCas9 (Feldan Therapeutics) Delivery System CM18-PTD4 Delivery System Subtype Amphiphilic peptide Guide g-11_C9 Vector Model Species Human Model Name Primary Airway Epithelia Application Method In Media Application Site Dosage [RNP]: 2.5 µM; [gRNA]: 2.0 μM; [Peptide]: 40uM Injection Frequency Injection Rate Injection Volume Days post injection 72 hours Editor Format RNP Antidote Id Antidote Description Measured Values Samples Size: 1   Replicate Result (Editing Efficiency) Measurement Units: % indel Mean 11.00  1 11.0