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ExperimentCre Recombinase dose escalation study in Ai9 mice
Experiment ConditionMock, 1e12vg, Male
Assay Description: Delivery efficency was calculated by measuring fluorescent intensity in tdTomato+ cells from multiple images and sections in liver, heart, skeletal muscle
Tissue Measured:skeletal muscle tissue
Measurement Type:Delivery Efficiency
Record ID15000000995

Editor
Delivery System
Delivery System Subtype
Guide
Vector

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Siteliver and heart
Dosage
Injection Frequency
Injection Rate
Injection Volume
Days post injection4 weeks
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 1
 
Replicate Result (Delivery Efficiency)
Measurement Units: Corrected total cell fluorescence
Mean 0.0 
1 0.0 
  

Publication Title
Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. NCBI