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ExperimentCre Recombinase dose escalation study in Ai9 mice
Experiment ConditionMock, 1e12vg, Male
Assay Description: Delivery efficency in brain was calculated by counting the total number of TdTomato+ neurons and total number of NeuN+ cells
Tissue Measured:cerebral cortex
Cell Type :neuron
Measurement Type:Delivery Efficiency
Record ID15000000998

Editor
Delivery System
Delivery System Subtype
Guide
Vector

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Sample Age8 weeks
Sample SexMale

Application Methodintravenous
Application Siteliver and heart
Dosage
Injection Frequency
Injection Rate
Injection Volume
Days post injection4 weeks
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 1
 
Replicate Result (Delivery Efficiency)
Measurement Units: % of cells
Mean 0.0 
1 0.0 
  

Publication Title
Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. NCBI