Development System
FSD114d1 | SCGE Toolkit
Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
    
    
    
    
    
        
        
        
        
            
                
                    
                        
                        
                        
                        
                        
                        
                            
                        
                    
                        
                        
                            
                            
                            
                        
    
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            | Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus |  | FSD114d1 |  
                | Editing efficiency was assessed using Next Generation Sequencing |  
                |  |  
                | Editing Efficiency |  | 15000002963 |  | 
 |  | SpCas9 (Feldan Therapeutics) |  | FSD114d1 |  | Amphiphilic peptide |  | 3849 C>T loci |  |  |  | 
 |  | Human |  | Primary Airway Epithelia |  | 
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ribonucleoprotein (RNP) |  |  |  |  |  | 
 |  
                | Measured Values |  
                | Samples Size: | 6 |  |  |  
                
                
             
                 
                     
                     
                      
                
                | Mean | 4.81  |  
                
                | 1 | 1.04  |  
                
                | 2 | 1.43  |  
                
                | 3 | 11.69  |  
                
                | 4 | 11.76  |  
                
                | 5 | 1.85  |  
                
                | 6 | 1.09  |  |  |  |