Contact SCGE




SCGE Consortium Home   |  About SCGE Toolkit   |  Contact Us   |  Citing the Toolkit   |  License  
 
Filters ..
Delivery Systems
 AAV
Models
 Human kidney organoid (iPSC-derived)
Sex
 Male
  Vectors
 AAV2/2CMVeGFP
 AAV2/8CMVeGFP
 AAV2/9CMVeGFP
Select experimental variable to highlight records on the chart: 
 

Note: Hover over the bars to view additional information

Loading...

Results

Biomarker_assays_to_evaluate_toxicity_induced_by_AAVs_in_iPS_cell_derived_kidney_organoids.
Other Measurement
Record Id Condition Sex Model Delivery Vector Dosage Biomarker Detection KIM-1 (pg/mL) Image
15000003428 Control Male Human kidney organoid (iPSC-derived) control
15000003429 AAV2/2 Male Human kidney organoid (iPSC-derived) AAV AAV2/2CMVeGFP MOI=10^5
15000003430 AAV2/8 Male Human kidney organoid (iPSC-derived) AAV AAV2/8CMVeGFP MOI=10^5
15000003431 AAV2/9 Male Human kidney organoid (iPSC-derived) AAV AAV2/9CMVeGFP MOI=10^5

Biomarker assays to evaluate toxicity and inflammation induced by AAVs in kidney organoids. BJFF samples showing KIM-1 levels using Luminex (Bio-plex 200). Groups were divided based on infection from Day 21 - 24 and Day 25 – 28.