Experiment Large animal testing of AAV9 vs AAVcc47 (Asokan lab's novel capsid) via intramuscular administration to rhesus macaques Experiment Condition AAV9 Assay Description: Tissue Measured: liver Measurement Type: Delivery Efficiency Record ID 15000005724 Editor SaCas9 Delivery System Delivery System Subtype Guide JCR183 Vector AAV9-SaCas9/guide DMD; Model Species Model Name Sample Age ~3-4 months of age Application Method intramuscular Application Site left quadriceps Dosage 3e13vg/NHP dose injected in the quad Injection Frequency Once Injection Rate Injection Volume ~1-2 ml Days post injection 4 weeks Editor Format AAV encoded Antidote Id Antidote Description Measured Values Samples Size: 4   Replicate Result (Delivery Efficiency) Measurement Units: SaCas9/globin copies Mean 86028.5  1 81721  2 117307  3 75475  4 69611