Ai9-SauSpyCas9 mouse | SCGE Toolkit>

SCGE ID	13000000042
Name	Ai9-SauSpyCas9 mouse
Official Name	B6.Cg-Gt(ROSA)26Sor^{em1(CAG-tdTomato)JaHe}
Alias	SaSp Ai9, SaSp single-guide Ai9
Species	Mouse
Type	Animal
Description	Ai9-SauSpyCas9 is a version of Ai9 that has a single guide RNA sites on both sides of the STOP cassette. This is a Cre reporter allele that has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. Ai9 mice express robust tdTomato fluorescence following Cre-mediated recombination.

Source	Baylor College of Medicine

This Model System: Ai9-SauSpyCas9 mouse is being used

Project	Initiative	Contact PI
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice	Animal Reporter and Testing Center Initiative	Jason D Heaney, PhD (Baylor College of Medicine)

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