Summary

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Projects & Experiments

This Delivery System: FSD262 is being used ...

Project	Initiative	Contact PI
Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides Experiments Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells	Delivery Systems	Paul B McCray, Jr, MD (University of Iowa)
Base Editing in Rhesus Airway Epithelial Experiments Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.	Collaborative Opportunity Fund	Paul B McCray, Jr, MD Alice F Tarantal, PhD David Guay, PhD David R Liu, PhD (University of Iowa)