Delivery System: RNP-NC-RVG
Summary
| SCGE ID | 12000000190 |
| Name | RNP-NC-RVG |
| Description | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a RVG peptide YTIWMPENPRPGTPCDIFTNSRGKRASNG which specifically interacts withthe N-acetylecholine receptor (AchR) on neuronal cells, which mediates NP entry |
| Type | Nanoparticle |
| Subtype | polymer-RNP nanocapsule |
| Source | Gong Lab |
| Nanoparticle Size | 38 nm |
| Zeta Potential | 3 mV |
Projects & Experiments
This Delivery System: RNP-NC-RVG is being used ...| Project | Initiative | Contact PI | |
|---|---|---|---|
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Animal Reporter and Testing Center |
Stephen A Murray, PhD
(Jackson Laboratory) |
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