SCGE ID11000000118
SymbolAlt-R® S.p. Cas9 Nuclease V3
DescriptionRecombinant S. pyogenes Cas9 nuclease, purified from an E. coli strain expressing the nuclease. Contains nuclear localization sequence (NLS) and C-terminal 6-His tag. Provided in solution at 10 µg/µL. 100 µg of Cas9 nuclease = 610 pmol.
SpeciesStreptococcus pyogenes
TypeCas Nuclease
SubtypeCas9

ActivityDouble strand cleavage
Substratedouble stranded DNA
DSB Cleavage TypeBlunt
PAM3' NGG
FusionNLS

SourceIntegrated DNA Technologies


This Genome Editor: Alt-R® S.p. Cas9 Nuclease V3 is being used
Project Initiative Contact PI
Delivery Systems Initiative Paul B McCray, Jr, MD
(University of Iowa)
NIH Report