Testing virus region 4 (VR4) mutant cross-species compatible Adeno Associated Viruses (ccAAVs) in mice. |
AAVcc47-mCherry |
Native fluorescence was quantified using Image J. For each animal, 6 images were taken from 2 sections and used to calculate corrected total cell fluorescence using the formula: Integrated Density – (Area of selected image X Mean fluorescence of background readings). |
liver |
Delivery Efficiency |
15000000344 |
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AAVcc47-mCherry; |
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Mouse |
C57BL/6 |
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intravenous |
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5e13Â vg/kg |
once |
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200 microliters |
4 weeks |
AAV vector encoded |
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Measured Values |
Samples Size: | 3 |
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Mean |
9486916570.81  |
1 |
9906108957.14167  |
2 |
9335568209.57333  |
3 |
9219072545.71278  |
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Representative image of AAVcc47-mCherry delivery in liver |
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