Contact SCGE




SCGE Consortium Home   |  About SCGE   |  Contact Us   |  Citing the Toolkit   |  License  

Experiment: Delivery of RNP containing chemically modified crRNA C20 with chemically modified tracrRNA T2-PS to determine the RNP distribution in TLR-MCV mouse brain

PI:   Erik J Sontheimer, PhD 
 

Chemically modified crRNA and tracrRNA were injected into the striatum of TLR-MCV mice and the distribution of RNP was imaged.
Delivery Assays: - Delivery and uptake testing of C20-Cy3/T2-PS (red fluorescence) and SpyCas9 by immunohistochemical staining (green fluorescecnce) after intrastriatal injections

Organ System Overview


 
Sp_c20_MCV1a/Sp_t2_5-3_PS-tail
Legend:  
Delivery Efficiency
Editing Efficiency
Target Tissue
Not Available
 

 
Analyze Data Sets Available for this Experiment
Nervous
  Brain (unspecified)