Cre Recombinase dose escalation study in Ai9 mice |
AAVcc47-CMV-Cre, 1e11vg, Male |
Delivery efficency was calculated by measuring fluorescent intensity in tdTomato+ cells from multiple images and sections in liver, heart, skeletal muscle |
heart |
Delivery Efficiency |
15000000981 |
|
Cre recombinase |
AAV |
Viral vector |
|
AAVcc47-CMV-Cre; |
|
Mouse |
B6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J |
|
intravenous |
liver and heart |
1e11vg |
once |
|
200 microliters |
4 weeks |
AAV vector encoded |
|
|
|
Measured Values |
Samples Size: | 3 |
|
Mean |
675732931.34  |
1 |
633518715.181083  |
2 |
878265711.533583  |
3 |
515414367.303083  |
| |
|