Cre recombinase | SCGE Toolkit

SCGE ID	11000000125
Symbol	Cre recombinase
Description	Cre recombinase delivered by AAV (see vector details)
Species	P1 Bacteriophage
Type	Recombinase
Subtype	Cre recombinase
Alias	Cre

Activity	loxP recombination
Substrate	double stranded DNA
PAM	not applicable
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RRID

This Genome Editor: Cre recombinase is being used ...

Project	Initiative	Contact PI
Novel AAVs Engineered for Efficient and Noninvasive Cross-Species Gene Editing Throughout the Central Nervous System Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro	Delivery Systems	Benjamin E Deverman, PhD (Broad Institute)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice Experiments Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing. Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice	Animal Reporter and Testing Center	Jason D Heaney, PhD (Duke University)
Evolving High Potency AAV Vectors for Neuromuscular Genome Editing Experiments Cre Recombinase dose escalation study in Ai9 mice	Delivery Systems	Aravind Asokan, PhD (Duke University)

Genome Editor: Cre recombinase