Development System AAVcc47-CMV-Cre, 1e12vg, Female | SCGE Toolkit Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
Cre Recombinase dose escalation study in Ai9 mice
AAVcc47-CMV-Cre, 1e12vg, Female
Delivery efficency in brain was calculated by counting the total number of TdTomato+ neurons and total number of NeuN+ cells
cerebral cortex
neuron
Delivery Efficiency
15000000991
Cre recombinase
AAV
Viral vector
AAVcc47-CMV-Cre ;
Mouse
B6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J
intravenous
liver and heart
1e12vg
once
200 microliters
4 weeks
AAV vector encoded
Measured Values
Samples Size: 2
Mean
2.79 
1
2.829658343 
2
2.745178815 
Publication Title
Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. NCBI
Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. NCBI