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Filters ..
  Tissues
Liver and Biliary
  • Liver  (TARGET)
Cardiovascular
  • Heart  (TARGET)
Editors
 SaCas9-Lagor
Models
 Ai9 mouse
  Sex
 Female
 Male
  Vectors
 AAV9-Ai9-sgRNA1-CB-SaCas9
 AAV9-Ai9-sgRNA2-CB-SaCas9
 AAVcc47-Ai9-sgRNA1-CB-SaCas9
 AAVcc47-Ai9-sgRNA2-CB-SaCas9
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Results

Comparing_CRISPR/Cas9_gene_editing_efficencies_between_AAV9_and_AAVcc47_in_Ai9_mice_with_a_1:1_Cas9_to_sgRNA_ratio_(CB_promoter)_
Editing Efficiency
Record Id Condition Tissue Sex Editor Model Vector Dosage Injection Frequency Editing Efficiency % of cells Image
15000001005 AAV9, Male liver (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1-CB-SaCas9; AAV9-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001006 AAV9, Male heart (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1-CB-SaCas9; AAV9-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001007 AAV9, Female liver (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1-CB-SaCas9; AAV9-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001008 AAV9, Female heart (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1-CB-SaCas9; AAV9-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001009 AAVcc47, Male liver (TARGET) Male SaCas9-Lagor Ai9 mouse AAVcc47-Ai9-sgRNA1-CB-SaCas9; AAVcc47-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001010 AAVcc47, Male heart (TARGET) Male SaCas9-Lagor Ai9 mouse AAVcc47-Ai9-sgRNA1-CB-SaCas9; AAVcc47-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001011 AAVcc47, Female liver (TARGET) Female SaCas9-Lagor Ai9 mouse AAVcc47-Ai9-sgRNA1-CB-SaCas9; AAVcc47-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001012 AAVcc47, Female heart (TARGET) Female SaCas9-Lagor Ai9 mouse AAVcc47-Ai9-sgRNA1-CB-SaCas9; AAVcc47-Ai9-sgRNA2-CB-SaCas9 1e12vg each vector mixed 1:1 once
15000001013 Mock liver (TARGET) Male Ai9 mouse
15000001014 Mock heart (TARGET) Male Ai9 mouse