Experiment Large animal testing of AAV9 vs AAVcc47 (Asokan lab's novel capsid) via intravenous administration to rhesus macaques Experiment Condition AAVcc47 Assay Description: Tissue Measured: liver Measurement Type: Delivery Efficiency Record ID 15000005721 Editor SaCas9 Delivery System AAV Delivery System Subtype Viral vector Guide JCR183 Vector AAVcc47-SaCas9/guide DMD; Model Species Model Name Sample Age ~3-4 months of age Application Method intravenous Application Site systemic Dosage 1. 3e13vg/kg (1~1.5kg body weight) Injection Frequency Once Injection Rate Injection Volume ~1-2 ml Days post injection 4 weeks Editor Format AAV encoded Antidote Id Antidote Description Measured Values Samples Size: 3   Replicate Result (Delivery Efficiency) Measurement Units: SaCas9/globin copies Mean 53989.33  1 83639  2 47065  3 31264