Development System
AAVcc47 | SCGE Toolkit
Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
| Large animal testing of AAV9 vs AAVcc47 (Asokan lab's novel capsid) via intramuscular administration to rhesus macaques |
| AAVcc47 |
|
| skin of body |
| Delivery Efficiency |
| 15000005730 |
|
| SaCas9 |
|
|
| JCR183 |
| AAVcc47-SaCas9/guide DMD; |
|
|
|
|
| ~3-4 months of age |
|
| intramuscular |
| left quadriceps |
| 3e13vg/NHP dose injected in the quad |
| Once |
|
| ~1-2 ml |
| 4 weeks |
| AAV encoded |
|
|
|
| Measured Values |
| Samples Size: | 4 |
| |
| Mean |
19381.5  |
| 1 |
23534  |
| 2 |
19217  |
| 3 |
18437  |
| 4 |
16338  |
| |
|