eVLP | SCGE Toolkit

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Summary Projects & Experiments

SCGE ID	12000000212
Name	eVLP
Description	engineered virus like particles
Type	Virus Like Particle

Source	Liu Lab

Publication Title
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins. NCBI

This Delivery System: eVLP is being used ...

Project	Initiative	Contact PI
Delivery Technologies for In Vivo Genome Editing Experiments Pcsk9 adenine base editor efficiency in liver and nonliver tissue On-target editing compared to 14 circle-seq nominated off-target sites of adenine base editor delivered by BE-eVLP vs AAV in the C57BL/6 liver	Delivery Systems	Elliot L. Chaikof, MD, PhD (Beth Israel Deaconess Medical Center)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice Experiments Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver	Animal Reporter and Testing Center	Jason D Heaney, PhD (Baylor College of Medicine)