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Filters ..
  Tissues
Liver and Biliary
  • Liver  (TARGET)
Cardiovascular
  • Heart  (TARGET)
Editors
 SaCas9-Lagor
Models
 Ai9 mouse
  Sex
 Female
 Male
  Vectors
 AAV9-Ai9-sgRNA1 + sgRNA2
 AAV9-CMV-SaCas9
 AAVcc47-Ai9-sgRNA1 + sgRNA2
 AAVcc47-CMV-SaCas9
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Results

Comparing_CRISPR/Cas9_gene_editing_efficencies_between_AAV9_and_AAVcc47_in_Ai9_mice_with_a_1:1_cas9_to_sgRNA_ratio_(CMV_promoter)_
Editing Efficiency
Record Id Condition Tissue Sex Editor Model Vector Dosage Injection Frequency Editing Efficiency % of cells Image
15000001015 AAV9, Male liver (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1 + sgRNA2; AAV9-CMV-SaCas9 1.5e12vg each vector mixed 1:1 once
15000001016 AAV9, Male heart (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1 + sgRNA2; AAV9-CMV-SaCas9 1.5e12vg each vector mixed 1:1 once
15000001017 AAV9, Female liver (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1 + sgRNA2; AAV9-CMV-SaCas9 1.5e12vg each vector mixed 1:1 once
15000001018 AAV9, Female heart (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-Ai9-sgRNA1 + sgRNA2; AAV9-CMV-SaCas9 1.5e12vg each vector mixed 1:1 once
15000001019 AAVcc47, Male liver (TARGET) Male SaCas9-Lagor Ai9 mouse AAVcc47-Ai9-sgRNA1 + sgRNA2; AAVcc47-CMV-SaCas9 1.5e12vg each vector mixed 1:1 once
15000001020 AAVcc47, Male heart (TARGET) Male SaCas9-Lagor Ai9 mouse AAVcc47-Ai9-sgRNA1 + sgRNA2; AAVcc47-CMV-SaCas9 1.5e12vg each vector mixed 1:1 once
15000001021 Mock liver (TARGET) Ai9 mouse
15000001022 Mock heart (TARGET) Ai9 mouse