Experiment Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Experiment Condition Arm 3: uninjected control Assay Description: Confocal Imaging of mouse cochlea, direct fluorescence RFP (tdTomato) compared to Hoechst stained nuclei. Tissue Measured: base of cochlear canal Measurement Type: Editing Efficiency Record ID 15000001304 Editor Delivery System Delivery System Subtype Guide Vector Model Species Mouse Model Name B6.Cg-Gt(ROSA)26Sor^tm14(CAG-tdTomato)Hze/J Sample Age 8 weeks Sample Sex Mixed Application Method uninjected control Application Site inner ear Dosage Injection Frequency none Injection Rate Injection Volume none Days post injection 6 days Editor Format no editor Antidote Id Antidote Description Measured Values Samples Size: 2   Replicate Result (Editing Efficiency) Measurement Units: Signal Mean 2 of 2 absent  1 absent  2 absent