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Filters ..
Editors
 ABE8e
Guide Target Locus
 CCR5
  Guides
 ABE8e-Cas9 Guide 1 CCR5 Rhesus
 ABE8e-Cas9 Guide 10 CCR5 Rhesus
 ABE8e-Cas9 Guide 2 CCR5 Rhesus
 ABE8e-Cas9 Guide 3 CCR5 Rhesus
 ABE8e-Cas9 Guide 4 CCR5 Rhesus
 ABE8e-Cas9 Guide 5 CCR5 Rhesus
 ABE8e-Cas9 Guide 6 CCR5 Rhesus
 ABE8e-Cas9 Guide 7 CCR5 Rhesus
 ABE8e-Cas9 Guide 8 CCR5 Rhesus
 ABE8e-Cas9 Guide 9 CCR5 Rhesus
Delivery Systems
 SE Cell Line 4D-Nucleofector™ X Kit S
Models
 Primary skin fibroblasts (Rhesus Macaque)
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Results

Rhesus_macaque_CCR5_gRNA_screening_using_ABE8e-Cas9
Editing Efficiency
Record Id Condition Editor Model Delivery Target Locus Guide Dosage Editing Efficiency % of reads Image
15000002939 ABE8e-Cas9 Guide 1 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 1 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002940 ABE8e-Cas9 Guide 2 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 2 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002941 ABE8e-Cas9 Guide 3 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 3 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002942 ABE8e-Cas9 Guide 4 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 4 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002943 ABE8e-Cas9 Guide 5 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 5 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002944 ABE8e-Cas9 Guide 6 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 6 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002945 ABE8e-Cas9 Guide 7 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 7 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002946 ABE8e-Cas9 Guide 8 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 8 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002947 ABE8e-Cas9 Guide 9 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 9 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP
15000002948 ABE8e-Cas9 Guide 10 ABE8e Primary skin fibroblasts (Rhesus Macaque) SE Cell Line 4D-Nucleofector™ X Kit S CCR5 ABE8e-Cas9 Guide 10 CCR5 Rhesus 26 µM gRNA and ABE8e-Cas9 11 µM in a total volume of 10 ml RNP