SCGE ID14000000040
DescriptionNovel engineered AAV BI28 variant expressing S. aureus Cas9 driven by the glial fibrillary acidic protein (GFAP) promoter
TypeViral Vector

SourceDeverman Lab

Genome SerotypeAAV2
Capsid SerotypeAAV BI28 (novel engineered variant)
Capsid VariantBI28: 7-mer peptide insertion (VP1 588-589) within AAV9 K449R

Titer MethodddPCR, average of two titers using ITR and WPRE primers

This Vector/Format: BI28:AAV-GFAP-SaCas9-WPRE3-pA is being used ...
Project Initiative Contact PI
Delivery Systems Initiative Benjamin E Deverman, PhD
(Broad Institute)
NIH Report
Animal Reporter and Testing Center Initiative Jason D Heaney, PhD
(Baylor College of Medicine)
NIH Report