Representative coronal brain images from an Ai14 reporter mouse intrastriatally injected with cell penetrating peptide (CPP) decorated nanocages (NC-CPP) carrying CRISPR Cas9/sgRNA ribonucleoprotein. The brain sections are shown in rostrocaudal (top to bottom) anatomical order. The colors correspond to tdTomato-expressing, genome-edited cells (red; white arrows pointing to edited area) with NeuN+ neurons (green), GFAP+ astrocytes (pink), and DAPI labelled nuclei (blue).