Delivery System: RNP-NC-CPP
Summary
SCGE ID | 12000000188 |
Name | RNP-NC-CPP |
Description | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a cell penetrating peptide (CPP) from the TAT peptide (GRKKRRQRRRPQ) which lacks cell-type specficity |
Type | Nanoparticle |
Subtype | polymer-RNP nanocapsule |
Source | Gong Lab |
Nanoparticle Size | 34 nm |
Zeta Potential | 3 mV |