SCGE ID12000000188
DescriptionThe nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a cell penetrating peptide (CPP) from the TAT peptide (GRKKRRQRRRPQ) which lacks cell-type specficity
Subtypepolymer-RNP nanocapsule

SourceGong Lab

Nanopartical Size34 nm
Zeta Potential3 mV


This Delivery System: RNP-NC-CPP is being used
Project Initiative Contact PI
Delivery Systems Initiative Shaoqin (Sarah) Gong, PhD
(University of Wisconsin-Madison)
NIH Report
Animal Reporter and Testing Center Initiative Stephen A Murray, PhD
(Jackson Laboratory)
NIH Report