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Filters ..
Tissues
Liver and Biliary
  • Liver
Editors
 CleanCap┬« Fluc
  Delivery Systems
 113-O12B
 306-O12B
 306-S10
Models
 C57BL/6J mouse

Results

Testing_new_LNPs_(lipid_nanoparticles)_for_delivery_of_Fluc_mRNA_in_adult_mice
Delivery Efficiency
Record Id Condition Tissue Editor Model Delivery Dosage Injection Frequency Delivery Efficiency Signal Image
15000000591 306-O12B liver CleanCap® Fluc C57BL/6J mouse 306-O12B 10 ug per mouse once
15000000592 113-O12B liver CleanCap® Fluc C57BL/6J mouse 113-O12B 10 ug per mouse once
15000000593 306-S10 liver CleanCap® Fluc C57BL/6J mouse 306-S10 10 ug per mouse once

In vivo luciferase assay for mRNA delivery. Selected LNPs were mixed with Fluc mRNA and injected into adult wild type mice via i.v. injection at 10 ug mRNA per mouse. The luciferase expression was evaluated 6 h later by live animal bioluminescence imaging.