Summary

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Projects & Experiments

This Delivery System: 306-S10 is being used ...

Project	Initiative	Contact PI
Efficient In Vivo RNP-Based Gene Editing in the Sensory Organ Inner Ear Using Bioreducible Lipid Nanoparticles Experiments Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice	Delivery Systems Initiative	Zheng-Yi Chen, PhD (Massachusetts Eye & Ear Infirmary)
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) Experiments Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear	Animal Reporter and Testing Center Initiative	Stephen A Murray, PhD (Jackson Laboratory)