Contact SCGE




SCGE Consortium Home   |  About SCGE   |  Contact Us   |  Citing the Toolkit   |  License  

Experiment: Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain

PI:   Erik J Sontheimer, PhD 
 

Chemically modified crRNA and tracrRNA were injected into the intra-striatum of mTmG reporter mice and activation of GFP expression was imaged.
Editing Assay: - Editing efficiency determined by immunohistochemical staining for GFP.

Organ System Overview
Legend:  
Delivery Efficiency
Editing Efficiency
Target Tissue
Not Studied


 
Sp_c0_mTmG/Sp_t2 + S10 shuttle peptide
 

 
Analyze Data Sets Available for this ExperimentDeliveryEditing
Nervous
  Brain n/a