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Filter Results ..
  Tissues
Liver and Biliary
  • Liver (unspecified)  (TARGET)
Cardiovascular
  • Heart (unspecified)  (TARGET)
Editors
 SaCas9-Lagor
Models
 Ai9 mouse
  Sex
 Female
 Male
  Vectors
 AAV9-CMV-SaCas9
 AAV9_pTR_self comp 2xU6-Ai9 guides
 AAVcc47_pTR_self comp 2xU6-Ai9 guides
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Results

Comparing_CRISPR/Cas9_gene_editing_efficencies_between_AAV9_and_AAVcc47_in_Ai9_mice_with_a_1:1_Cas9_to_sgRNA_ratio_(CMV_promoter)_and_self_complementary_sgRNA_vector.__
Editing Efficiency
Record Id Condition Tissue Sex Editor Model Vector Dosage Injection Frequency Editing Efficiency % of cells Image
15000001033 AAV9, Male liver (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAV9_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001034 AAV9, Male heart (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAV9_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001035 AAV9, Female liver (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAV9_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001036 AAV9, Female heart (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAV9_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001037 AAVcc47, Male liver (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAVcc47_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001038 AAVcc47, Male heart (TARGET) Male SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAVcc47_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001039 AAVcc47, Female liver (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAVcc47_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001040 AAVcc47, Female heart (TARGET) Female SaCas9-Lagor Ai9 mouse AAV9-CMV-SaCas9; AAVcc47_pTR_self comp 2xU6-Ai9 guides 2e12vg of CMV Sacas9 vector and 2e12vg of the self complementary sgRNA vector once
15000001041 Mock heart (TARGET) Ai9 mouse