Development System Testing preparation for validation at The Jackson Laboratory Small Animal Testing Center | SCGE Toolkit Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
Experiment: Testing preparation for validation at The Jackson Laboratory Small Animal Testing Center
PI:
Erik J Sontheimer, PhD
Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
Editing Assay:
- Editing efficiency determined by immunohistochemical staining for GFP.