SCGE ID13000000031
NameAi14 mouse (congenic)
Official NameB6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J
DescriptionAi14 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. The att site flanked neo selection cassette has been removed in this strain.

SourceThe Jackson Laboratory

TransgeneAi9 (CAG-lox-stop-lox-tdTomato)
Transgene DescriptionCAG-loxP-stop-loxP-tdtomato reporter cassette which is activated by Cre recombination or double strand breaks on both sides of the stop cassette and NHEJ repair
Annotated Mapaddgene-plasmid-22799-sequence-115994.gbk

Publication Title
Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice. NCBI

Publication Title
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain.  NCBI

This Model System: Ai14 mouse (congenic) is being used ...
Project Initiative Contact PI
Delivery Systems Initiative Zheng-Yi Chen, PhD
(Massachusetts Eye & Ear Infirmary)
NIH Report