Model System: Ai14 mouse (congenic)
Summary
| SCGE ID | 13000000031 |
| Name | Ai14 mouse (congenic) |
| Official Name | B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J |
| Species | Mouse |
| Type | Animal |
| Description | Ai14 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. The att site flanked neo selection cassette has been removed in this strain. |
| Source | The Jackson Laboratory |
| RRID | RRID:IMSR_JAX:007914 |
| Transgene | Ai9 (CAG-lox-stop-lox-tdTomato) |
| Transgene Description | CAG-loxP-stop-loxP-tdtomato reporter cassette which is activated by Cre recombination or double strand breaks on both sides of the stop cassette and NHEJ repair |
| Reporter | tdTomato |
| Annotated Map | addgene-plasmid-22799-sequence-115994.gbk |
Associated Publications |
| Publication Title |
|---|
| Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice. NCBI |
Related Publications |
| Publication Title |
|---|
| A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. NCBI |
Projects & Experiments
This Model System: Ai14 mouse (congenic) is being used ...| Project | Initiative | Contact PI | |
|---|---|---|---|
| Delivery Systems Initiative |
Zheng-Yi Chen, PhD
(Massachusetts Eye & Ear Infirmary) |
|