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Cas9 ribonucleoprotein delivery targeted to kidney epithelium Project - [In Vitro] [Delivery Systems, Collaborative Opportunity Fund, Biological Effects] Matched Fields: category : Project initiative : Collaborative Opportunity Fund Wilson Ross , Freedman Benjamin S Last Updated Date: 2024-01-16 Show Experiments (1) Podocyte-specific gene editing in human kidney organoids
Comparing the efficiency and cellular impact of non-viral, hepatocyte-targeted delivery vehicles with viral-mediated gene delivery in a microphysiological liver on chip platform Project - [In Vitro] [Delivery Systems, Collaborative Opportunity Fund, Biological Effects] Matched Fields: category : Project initiative : Collaborative Opportunity Fund Gong Sarah , Wilson Ross , Kiani Samira Last Updated Date: 2023-12-18 Show Experiments (3) Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
Base Editing in Rhesus Airway Epithelial Project - [In Vivo, In Vitro] [Delivery Systems, Genome Editors, Collaborative Opportunity Fund] Matched Fields: category : Project initiative : Collaborative Opportunity Fund Liu David , McCray Paul , Tarantal Alice , Guay David Last Updated Date: 2023-03-15 Show Experiments (7) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9 Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway

3 results in Projects

Type	Subtype	Name	Description	Source	Last Updated Date	View Associated...
		Cas9 ribonucleoprotein delivery targeted to kidney epithelium			2024-01-16	Show Experiments (1) Podocyte-specific gene editing in human kidney organoids
		Comparing the efficiency and cellular impact of non-viral, hepatocyte-targeted delivery vehicles with viral-mediated gene delivery in a microphysiological liver on chip platform			2023-12-18	Show Experiments (3) Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
		Base Editing in Rhesus Airway Epithelial			2023-03-15	Show Experiments (7) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9 Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway