Delivery Systems

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140 results in Delivery Systems

113-O12B Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System combinatorial library cationic lipid nanoparticles Show Experiments (2) Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea
306-O12B Delivery System - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Delivery System Combinatorial library cationic lipid nanoparticles Show Experiments (7) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
306-O12B blank Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System Combinatorial library cationic lipid nanoparticles Show Experiments (2) Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
306-S10 Delivery System - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Delivery System combinatorial library cationic lipid nanoparticles Show Experiments (5) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
AAV Delivery System - [In Vivo, In Vitro] [Human, Mouse] Matched Fields: category : Delivery System See vector details Show Experiments (9) Cre Recombinase dose escalation study in Ai9 mice AAV Tropism project AAV tropism in kidney organoids derived from human pluripotent stem cells. AAV tropism in kidney organoids cultured under flow AAV2/2 transduction efficiencies in kidney organoids cultured under flow determined by FACS Biomarker assays to evaluate toxicity and inflammation induced by AAVs in ES cell derived kidney organoids. Biomarker assays to evaluate toxicity induced by AAVs in iPS cell derived kidney organoids. Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids. Evaluation of DNA damage, cellular toxicity and inflammatory markers following saCas9 and gRNAs delivery by AAV2 in kidney organoids.
AAV+Focused Ultrasound Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System See vector details Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
CM18-PTD4 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide Show Experiments (2) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
D10 Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
D237 Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
FS48 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
FS66d6 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD112 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD114 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD114d1 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
FSD115 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD115d1 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
FSD116d1 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD117D1 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
FSD118 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD121 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD122 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD132 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD147 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD159 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD160 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168 Disul. Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168 Scr. Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168 cyclic Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168D20 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
FSD168d10 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168d11 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168d12 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168d17 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD168d20 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide Show Experiments (1) Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD186 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD188 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD189 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD190 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD191 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD193 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD195 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
FSD196 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD197 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
FSD199 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD215 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD216 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD222 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD227 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD228 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD234 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD235 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD236 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD237 Delivery System - [In Vitro] [Human, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (5) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
FSD238 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
FSD239 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD240 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD259 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD260 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD262 Delivery System - [In Vitro] [Human, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (4) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
FSD283 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD284 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD285 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
FSD286 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD287 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD288 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD289 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD291 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD293 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD297 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD301 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
FSD303 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD304 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD305 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD306 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD307 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD308 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD310 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD315 Delivery System - [In Vivo, In Vitro] [Human, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (7) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
FSD316 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD317 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD318 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD319 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD321 Delivery System - [In Vitro] [Human, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (4) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
FSD322 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD323 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD329 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD330 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD331 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD332 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD333 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD334 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD335 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD339 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD341 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD347 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD359 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD360 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD361 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD362 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD363 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD364 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD365 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD366 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD367 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD368 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD57 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD57d1 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD57d3 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD57d4 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD57d5 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD57d6 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD63 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD63D1 Delivery System - [In Vitro] [Human, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
FSD67 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD94 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD95 Delivery System - [In Vitro] [Human, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
FSD96 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSD97 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX1 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX2 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX3 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX4 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX5 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX6 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX7 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
FSX8 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Lipofectamine 3000 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Lipid nanoparticle Show Experiments (2) Testing newly discovered Biggie Phage editors in human cells Testing AAV5 for activation of tdTomato in HEK293T cells
P3 Nucleofection Kit Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Nuceleofection kit to be used with Lonza's nucleofection system. Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
RNP-NC-CPP Delivery System - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Delivery System The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a cell penetrating peptide (CPP) from the TAT peptide (GRKKRRQRRRPQ) which lacks cell-type specficity Show Experiments (6) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
RNP-NC-RVG Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a RVG peptide YTIWMPENPRPGTPCDIFTNSRGKRASNG which specifically interacts withthe N-acetylecholine receptor (AchR) on neuronal cells, which mediates NP entry Show Experiments (2) Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain
RNP-NC-no ligand Delivery System - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Delivery System The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. Show Experiments (4) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
S10 Delivery System - [In Vivo, In Vitro] [Human, Mouse, Rhesus macaque] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (12) Testing Shuttle Peptides ability to deliver GFP-NLS to airway epithelia. Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells. Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
S10 Scr. Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
S10-MOD Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
S10D Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide used to deliver reagents to airway epithelia Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
S18 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide Show Experiments (2) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
S85 Delivery System - [In Vitro] [Human] Matched Fields: category : Delivery System Shuttle peptide Show Experiments (2) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
SE Cell Line 4D-Nucleofector™ X Kit S Delivery System - [In Vitro] [Rhesus macaque] Matched Fields: category : Delivery System For efficient transfection of difficult-to-transfect cell lines, e.g. Jurkat or MCF-7, in the 4D-NucleofectorTM X Unit (20 µL format). Show Experiments (2) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9 Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
eVLP Delivery System - [In Vivo] [Mouse] Matched Fields: category : Delivery System engineered virus like particles Show Experiments (3) Pcsk9 adenine base editor efficiency in liver and nonliver tissue On-target editing compared to 14 circle-seq nominated off-target sites of adenine base editor delivered by BE-eVLP vs AAV in the C57BL/6 liver Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver

140 results in Delivery Systems

Type	Subtype	Name	Description	Source	View Associated...
Nanoparticle	Cationic lipid	113-O12B	combinatorial library cationic lipid nanoparticles	Xu lab	Show Experiments (2) Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea
Nanoparticle	Cationic lipid	306-O12B	Combinatorial library cationic lipid nanoparticles	Xu lab	Show Experiments (7) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
Nanoparticle	Cationic lipid	306-O12B blank	Combinatorial library cationic lipid nanoparticles	Xu lab	Show Experiments (2) Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
Nanoparticle	Cationic lipid	306-S10	combinatorial library cationic lipid nanoparticles	Xu lab	Show Experiments (5) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
Viral vector	Adeno Associated Virus (AAV)	AAV	See vector details		Show Experiments (9) Cre Recombinase dose escalation study in Ai9 mice AAV Tropism project AAV tropism in kidney organoids derived from human pluripotent stem cells. AAV tropism in kidney organoids cultured under flow AAV2/2 transduction efficiencies in kidney organoids cultured under flow determined by FACS Biomarker assays to evaluate toxicity and inflammation induced by AAVs in ES cell derived kidney organoids. Biomarker assays to evaluate toxicity induced by AAVs in iPS cell derived kidney organoids. Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids. Evaluation of DNA damage, cellular toxicity and inflammatory markers following saCas9 and gRNAs delivery by AAV2 in kidney organoids.
Viral vector	Adeno Associated Virus	AAV+Focused Ultrasound	See vector details	Leong Lab	Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Amphiphilic peptide		CM18-PTD4	Shuttle peptide	Feldan Therapeutics (synthetic peptide from GL Biochem, 95% purity)	Show Experiments (2) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Amphiphilic peptide		D10		McCray Lab	Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Amphiphilic peptide		D237		McCray Lab	Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Amphiphilic peptide		FS48	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
Amphiphilic peptide		FS66d6	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD112	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD114	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD114d1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Amphiphilic peptide		FSD115	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD115d1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Amphiphilic peptide		FSD116d1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD117D1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
Amphiphilic peptide		FSD118	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD121	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD122	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD132	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD147	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD159	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD160	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168 Disul.	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168 Scr.	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168 cyclic	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168D20	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
Amphiphilic peptide		FSD168d10	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168d11	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168d12	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168d17	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD168d20	Shuttle peptide	Feldan Therapeutics (synthetic peptide from GL Biochem, 95% purity)	Show Experiments (1) Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD186	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD188	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD189	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD190	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD191	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD193	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD195	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Amphiphilic peptide		FSD196	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD197	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
Amphiphilic peptide		FSD199	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD215	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD216	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD222	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD227	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD228	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD234	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD235	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD236	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD237	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (5) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
Amphiphilic peptide		FSD238	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Amphiphilic peptide		FSD239	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD240	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD259	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD260	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD262	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (4) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
Amphiphilic peptide		FSD283	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD284	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD285	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
Amphiphilic peptide		FSD286	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD287	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD288	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD289	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD291	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD293	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD297	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD301	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
Amphiphilic peptide		FSD303	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD304	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD305	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD306	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD307	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD308	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD310	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD315	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (7) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
Amphiphilic peptide		FSD316	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD317	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD318	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD319	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD321	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (4) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
Amphiphilic peptide		FSD322	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD323	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD329	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD330	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD331	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD332	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD333	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD334	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD335	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD339	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD341	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD347	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD359	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD360	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD361	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD362	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD363	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD364	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD365	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD366	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD367	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD368	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD57	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD57d1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD57d3	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD57d4	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD57d5	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD57d6	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD63	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD63D1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
Amphiphilic peptide		FSD67	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD94	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD95	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (3) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus.
Amphiphilic peptide		FSD96	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSD97	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX1	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX2	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX3	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX4	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX5	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX6	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX7	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		FSX8	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Commercial Reagent		Lipofectamine 3000	Lipid nanoparticle	Thermo Fisher Scientific	Show Experiments (2) Testing newly discovered Biggie Phage editors in human cells Testing AAV5 for activation of tdTomato in HEK293T cells
Commercial Reagent		P3 Nucleofection Kit	Nuceleofection kit to be used with Lonza's nucleofection system.	Lonza #V4SP-3096	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Nanoparticle	Polymer-RNP nanocapsule	RNP-NC-CPP	The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a cell penetrating peptide (CPP) from the TAT peptide (GRKKRRQRRRPQ) which lacks cell-type specficity	Gong Lab	Show Experiments (6) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
Nanoparticle	Polymer-RNP nanocapsule	RNP-NC-RVG	The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a RVG peptide YTIWMPENPRPGTPCDIFTNSRGKRASNG which specifically interacts withthe N-acetylecholine receptor (AchR) on neuronal cells, which mediates NP entry	Gong Lab	Show Experiments (2) Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain
Nanoparticle	Polymer-RNP nanocapsule	RNP-NC-no ligand	The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA.	Gong Lab	Show Experiments (4) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
Amphiphilic peptide		S10	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (12) Testing Shuttle Peptides ability to deliver GFP-NLS to airway epithelia. Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells. Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
Amphiphilic peptide		S10 Scr.	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		S10-MOD	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		S10D	Shuttle peptide used to deliver reagents to airway epithelia	McCray Lab	Show Experiments (2) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Amphiphilic peptide		S18	Shuttle peptide	Feldan Therapeutics (synthetic peptide from GL Biochem, 95% purity)	Show Experiments (2) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Amphiphilic peptide		S85	Shuttle peptide	Feldan Therapeutics (synthetic peptide from GL Biochem, 95% purity)	Show Experiments (2) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Commercial Reagent		SE Cell Line 4D-Nucleofector™ X Kit S	For efficient transfection of difficult-to-transfect cell lines, e.g. Jurkat or MCF-7, in the 4D-NucleofectorTM X Unit (20 µL format).	Lonza	Show Experiments (2) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9 Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Virus Like Particle		eVLP	engineered virus like particles	Liu Lab	Show Experiments (3) Pcsk9 adenine base editor efficiency in liver and nonliver tissue On-target editing compared to 14 circle-seq nominated off-target sites of adenine base editor delivered by BE-eVLP vs AAV in the C57BL/6 liver Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver

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140 results in Delivery Systems

140 results in Delivery Systems