30 results in Genome Editors

AsCas12a (IDT and Feldan Therapeutics)

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor

CasΦ-2

Genome Editor  - [In Vitro] [Genome Editors] [Human]
Matched Fields: category : Genome Editor
Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies

CleanCap® Cas9 mRNA (5moU)

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.

CleanCap® Fluc

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
Firefly luciferase mRNA capped using CleanCap. It is polyadenylated, modified with 5-methoxyuridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.

SaCas9

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor

SaCas9 (AAV-SaCas9)

Genome Editor  - [In Vitro] [Biological Effects] [Human]
Matched Fields: category : Genome Editor
SaCas9 delivered by AAV-SaCas9 vector

SpyCas9-3xNLS

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal
Show Experiments (5)

ABE8e

Genome Editor  - [In Vitro] [Delivery Systems, Genome Editors, Collaborative Opportunity Fund] [Mouse, Rhesus macaque]
Matched Fields: category : Genome Editor
Tad8e deaminase fused to a nickase (D10A) spCas9

ABE8e

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
Catalytically impaired Cas fused to TadA deaminase

ABE8e-Cas12a

Genome Editor  - [In Vitro] [Delivery Systems, Genome Editors, Collaborative Opportunity Fund] [Rhesus macaque]
Matched Fields: category : Genome Editor
A-to-G base editor

Alt-R® S.p. Cas9 Nuclease V3

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems, Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
Recombinant S. pyogenes Cas9 nuclease, purified from an E. coli strain expressing the nuclease. Contains nuclear localization sequence (NLS) and C-terminal 6-His tag. Provided in solution at 10 µg/µL. 100 µg of Cas9 nuclease = 610 pmol.
Show Experiments (10)

Cre recombinase

Genome Editor  - [In Vitro] [Delivery Systems] [Human]
Matched Fields: category : Genome Editor
Cre recombinase delivered by plasmid (see vector details)

SaCas9

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor

SpyCas9-3xNLS

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems, Animal Reporter and Testing Center] [Human, Mouse]
Matched Fields: category : Genome Editor
SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal

CasΦ-1

Genome Editor  - [In Vitro] [Genome Editors] [Human]
Matched Fields: category : Genome Editor
Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies

CasΦ-3

Genome Editor  - [In Vitro] [Genome Editors] [Human]
Matched Fields: category : Genome Editor
Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies

GFP-NLS

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
Nuclear targeted GFP

SauCas9

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor

sNLS-SpCas9-sNLS

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems, Collaborative Opportunity Fund, Biological Effects, Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
SpCas9 with N- and C-terminal SV40 NLS

CleanCap® Cas9

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.

sNLS-SaCas9-sNLS Nuclease

Genome Editor  - [In Vitro] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
SaCas9 with N- and C-terminal SV40 NLS

TadA-8e V106W

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
Catalytically impaired Cas fused to evolved TadA deaminase (TadA-8e V106W)

30 results in Genome Editors

Type Subtype Name Description Source View Associated...
Cas Nuclease AsCas12a (Cpf1) AsCas12a (IDT and Feldan Therapeutics) IDT and Feldan Therapeutics
Cas Nuclease Cas12j CasΦ-2 Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies Jennifer Doudna Lab
Cas Nuclease Cas9 CleanCap® Cas9 mRNA (5moU) SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA. Trilink Biotechnologies
Reporter Bioluminescent CleanCap® Fluc Firefly luciferase mRNA capped using CleanCap. It is polyadenylated, modified with 5-methoxyuridine and optimized for mammalian systems. It mimics a fully processed mature mRNA. Trilink Biotechnologies
Recombinase Cre recombinase Cre recombinase Cre recombinase delivered by AAV (see vector details)
Cas Nuclease Cas9 SaCas9 Leong Lab
Cas Nuclease Cas9 SaCas9 (AAV-SaCas9) SaCas9 delivered by AAV-SaCas9 vector VectorBuilder
Cas Nuclease Cas9 SpyCas9-3xNLS SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal Sontheimer lab
Show Experiments (5)
Base Editor (SpCas9) Adenine base editor ABE8e Tad8e deaminase fused to a nickase (D10A) spCas9 David Liu Lab
Base Editor (SpCas9) Adenine base editor ABE8e Catalytically impaired Cas fused to TadA deaminase Liu Lab
Base Editor (Cas12a) Adenine base editor ABE8e-Cas12a A-to-G base editor Liu lab
Cas Nuclease Cas9 Alt-R® S.p. Cas9 Nuclease V3 Recombinant S. pyogenes Cas9 nuclease, purified from an E. coli strain expressing the nuclease. Contains nuclear localization sequence (NLS) and C-terminal 6-His tag. Provided in solution at 10 µg/µL. 100 µg of Cas9 nuclease = 610 pmol. Integrated DNA Technologies
Show Experiments (10)
Recombinase Cre recombinase Cre recombinase Cre recombinase delivered by plasmid (see vector details)
Cas Nuclease Cas9 SaCas9 Vector Encoded (ssaav5-sga+sgb-u1a.gfp)
Cas Nuclease Cas9 SaCas9
Cas Nuclease Cas9 SpyCas9-3xNLS SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal Sontheimer lab
Base Editor (SpCas9) Adenine base editor ABE8e-Cas9 A-to-G base editor Feldan Therapeutics
Cas Nuclease Cas9 SpCas9 IDT
Cas Nuclease Cas9 SpCas9 (Feldan Therapeutics) Feldan Therapeutics
Cas Nuclease AsCas12a (Cpf1) AsCas12a (Feldan Therapeutics) Feldan Therapeutics
Cas Nuclease Cas12j CasΦ-1 Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies Jennifer Doudna Lab
Cas Nuclease Cas12j CasΦ-3 Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies Jennifer Doudna Lab
Reporter Fluorescent protein GFP-NLS Nuclear targeted GFP Expressed From (Escherichia coli BL21DE3)
Cas Nuclease Cas9 SaCas9-Lagor William Lagor, Baylor College Of Medicine
Cas Nuclease Cas9 SauCas9
Cas Nuclease Cas9 sNLS-SpCas9-sNLS SpCas9 with N- and C-terminal SV40 NLS Aldevron 9212-5MG
Cas Nuclease Cas9 CleanCap® Cas9 SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA. Trilink Biotechnologies
Cas Nuclease Cas9 sNLS-SaCas9-sNLS Nuclease SaCas9 with N- and C-terminal SV40 NLS Aldevron
Cas Nuclease Cas9 SpCas9 HA-SV40NLS-SpCas9-SV40NLS Vector Encoded
Base Editor (SpCas9) Adenine base editor TadA-8e V106W Catalytically impaired Cas fused to evolved TadA deaminase (TadA-8e V106W) Chaikof Lab