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3849 45-5' Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
3849 C>T loci Guide - [In Vitro] [Human] Matched Fields: category : Guide Show Experiments (1) Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
AAVS1_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_10 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_11 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_12 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_13 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_14 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
ABE8e-Cas12a Guide 1 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 10 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 11 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 2 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 3 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 4 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 5 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 6 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 7 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 8 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 9 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas9 Guide 1 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 10 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 2 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 3 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 4 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 5 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 6 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 7 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 8 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 9 CCR5 Rhesus Guide - [In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Ai14 gRNA Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at multiple sites Show Experiments (3) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain
Ai9 SaCas9 Guide A Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Ai9 SaCas9 Guide B Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
B2M Guide - [In Vitro] [Human] Matched Fields: category : Guide Show Experiments (1) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
B2M_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
BCM_ssAAV5-Sa_sgB Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
BCM_ssAAV5-Sp_sgA Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
BCM_ssAAV5-Sp_sgB Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
CBLB_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_11 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_13 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_14 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_15 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_16 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_10 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_11 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_12 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_13 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_10 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_11 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Cas12j-GFP1 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP1 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP10 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP10 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP11 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP12 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP13 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP14 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP14 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP15 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP16 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP17 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP18 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP19 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP2 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP2 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP20 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP21 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP22 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP23 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP3 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP3 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP4 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP4 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP6 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP6 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP7 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP7 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP8 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP8 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP9 (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP9 (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas9-CFTR-R553X Guide - [In Vitro] [Human] Matched Fields: category : Guide CFTR-R553X Show Experiments (1) Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells
DMD low gRNA-1 Guide - [In Vitro] [Human] Matched Fields: category : Guide One of two low-off target gRNAs delivred by dual gRNA AAV vector pAAV[2gRNA]-mCherry-U6>{SagRNA#1*}:{SagRNA#2} Show Experiments (1) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids.
DMD low gRNA-2 Guide - [In Vitro] [Human] Matched Fields: category : Guide One of two low-off target gRNAs delivred by dual gRNA AAV vector AAV-gRNA Show Experiments (2) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids. Evaluation of DNA damage, cellular toxicity and inflammatory markers following saCas9 and gRNAs delivery by AAV2 in kidney organoids.
FAS_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
L1-modified Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (3) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
L1-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L2-modified Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (2) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
L2-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L3-modifed Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L3-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
LAG3_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_10 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
McCray_CFTR_Cas9_Guide1 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
NKG2A Guide - [In Vitro] [Human] Matched Fields: category : Guide gRNA targeting human NKG2A exon 3 Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells.
NT-sgRNA Guide - [In Vitro] [Human] Matched Fields: category : Guide Non targeting guide RNA Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
PDCD1_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_10 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_11 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_12 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_13 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_14 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_15 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_16 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_06 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_07 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_08 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_09 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Pcsk9 Exon 1 splice domain Guide - [In Vivo] [Mouse] Matched Fields: category : Guide Pcsk9 Exon 1 splice domain Show Experiments (2) Pcsk9 adenine base editor efficiency in liver and nonliver tissue Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver
R1-modified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R1-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R2-modified Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (2) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R2-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R26-1 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
R26-2 Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (3) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR-2) Mouse Model via Germline Editing
R26-3 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
R26-52 Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR-2) Mouse Model via Germline Editing
R26-59 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
R26-69 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
STS118 (TLR-MCV1a; Sp_t2-PS:Sp_c20_TLR_MCV1a) Guide - [In Vivo] [Mouse] Matched Fields: category : Guide Targets traffic light reporter transgene, CY3 labeled Show Experiments (1) Delivery of RNP containing chemically modified crRNA C20 with chemically modified tracrRNA T2-PS to determine the RNP distribution in TLR-MCV mouse brain
STS118 (TLR-MCV1a; Sp_t2:Sp_c20_TLR_MCV1a) Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets traffic light reporter transgene Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
STS119 (TLR-MCV1b; Sp_t2:Sp_c20_TLR_MCV1b) Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets traffic light reporter transgene Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
STS120 (TLR1; Sp_t2:Sp_c20_TLR1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets traffic light reporter transgene Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR1 reporter in human cells
STS134 (PCSK9b; Sp_t2:Sp_c20_PCSK9b) Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
STS135 (PCSK9c; Sp_t2:Sp_c20_PCSK9c) Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
STS159 (mTmG; Sp_t2-PS:Sp_c0_mTmG) Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2-PS:Sp_c20_mTmG) Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2:Sp_c0_mTmG) Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2:Sp_c20_mTmG) Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (4) Testing newly chemically modified crRNA and tracrRNA in mTmG mouse embryonic fibroblasts Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center Independent validation of Sontheimer delivery platform using heavily modified guide RNAs complexed with Cas9 proteins to deliver CRISPR/Cas9 to mouse brain
STS204 (DNMT1; Sp_t2:Sp_c20_Dnmt1) Guide - [In Vivo] [Mouse] Matched Fields: category : Guide For endogenous locus Show Experiments (2) Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center Independent validation of Sontheimer delivery platform using heavily modified guide RNAs complexed with Cas9 proteins to deliver CRISPR/Cas9 to mouse brain
STS204 (DNMT1; Sp_t41:Sp_c20_Dnmt1) Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
STS205 (BACE1; Sp_t41:Sp_c20_Bace1) Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
STS96 (PCSK9a; Sp_t2:Sp_c20_PCSK9a) Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
SaC9-g1 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
SaC9-g2 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
SaC9-g3 Guide - [In Vitro] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
SaLoxP1-modified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP1-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP2-modified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP2-unmodified Guide - [In Vitro] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Sa_Ai9_L Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016) Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Sa_Ai9_R Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016) Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
SapI-GG stuffer (CasΦ-1) Guide - [In Vitro] [Human] Matched Fields: category : Guide Non-targeting guide RNA targeting compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
SapI-GG stuffer (CasΦ-2) Guide - [In Vitro] [Human] Matched Fields: category : Guide Non-targeting guide RNA targeting compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
SapI-GG stuffer (CasΦ-3) Guide - [In Vitro] [Human] Matched Fields: category : Guide Non-targeting guide RNA targeting compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
SgaCas9-sgRNA1 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SgaCas9-sgRNA2 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SinCas9-sgRNA1 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SinCas9-sgRNA2 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SpaCas9-sgRNA1 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SpaCas9-sgRNA2 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SpyCas9 g-loxP2_C9 Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
SpyCas9-sgRNA1 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SubCas9-sgRNA1 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
SubCas9-sgRNA2 Guide - [In Vitro] [Human] Matched Fields: category : Guide Guide RNA targeting the human HBE promoter Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
TRAC_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_03 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_04 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_05 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRBC1_site_01 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRBC1_site_02 Guide - [In Vitro] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
g-11_C9 Guide - [In Vitro] [Human] Matched Fields: category : Guide sgRNA targeting CFTR exon 11 Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-38330_C12a Guide - [In Vitro] [Human] Matched Fields: category : Guide gRNA targeting HPRT locus Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-45_C12a Guide - [In Vitro] [Human] Matched Fields: category : Guide gRNA targeting CFTR inton-22-23 Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-loxP2_C9 Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
g-loxPbot_C12a Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at two sites Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
gRNA #8 Guide - [In Vivo, In Vitro] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (2) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
sg298 Guide - [In Vivo] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at multiple sites. 2'-O-Methyl at 3 first and last bases, 3' phosphorothioate bonds between first 3 and last 2 bases Show Experiments (4) Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
sg298 Guide - [In Vivo, In Vitro] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at multiple sites Show Experiments (3) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Podocyte-specific gene editing in human kidney organoids
sgAi9L Guide Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes
sgAi9L Guide - [In Vivo, In Vitro] [Human, Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells
sgAi9R Guide - [In Vivo, In Vitro] [Human, Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells

245 results in Guides

Organism	Compatibility	Name	Description	Source	View Associated...
Human	AsCas12a	3849 45-5'	Targets endogenous human locus	IDT	Show Experiments (1) Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Human	SpyCas9	3849 C>T loci		IDT	Show Experiments (1) Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Human	SpyCas9	AAVS1_site_01	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_02	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_03	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_04	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_05	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_06	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_07	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_08	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_09	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_10	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_11	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_12	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_13	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	AAVS1_site_14	Targets AAVS1 safe harbor locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 1 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 10 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 11 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 2 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 3 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 4 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 5 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 6 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 7 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 8 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a	ABE8e-Cas12a Guide 9 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 1 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 10 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 2 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 3 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 4 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 5 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 6 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 7 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 8 CCR5 Rhesus		David Liu lab's plasmid clone	Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9	ABE8e-Cas9 Guide 9 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Mouse	SpyCas9	Ai14 gRNA	This sgRNA targets the Ai9 and related transgenes at multiple sites	IDT	Show Experiments (3) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain
Mouse	SauCas9	Ai9 SaCas9 Guide A	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Mouse	SauCas9	Ai9 SaCas9 Guide B	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Human	SpyCas9	B2M		IDT	Show Experiments (1) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
Human	SpyCas9	B2M_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	B2M_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	B2M_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	B2M_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	B2M_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	B2M_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	B2M_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Mouse	SauCas9	BCM_ssAAV5-Sa_sgB	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Mouse	SpyCas9	BCM_ssAAV5-Sp_sgA	This sgRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Mouse	SpyCas9	BCM_ssAAV5-Sp_sgB	This sgRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Human	SpyCas9	CBLB_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CBLB_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CBLB_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CBLB_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CBLB_site_09	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_09	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_11	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_13	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_14	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_15	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CCR5_site_16	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_09	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_10	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_11	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_12	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CTLA4_site_13	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_10	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	CXCR4_site_11	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	CasΦ-1	Cas12j-GFP1 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP1 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP10 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP10 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP11 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP12 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP13 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP14 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP14 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP15 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP16 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP17 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP18 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP19 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP2 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP2 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP20 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP21 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP22 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP23 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP3 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP3 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP4 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP4 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1	Cas12j-GFP5 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP5 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP5 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP6 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP6 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP7 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP7 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP8 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP8 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	Cas12j-GFP9 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	Cas12j-GFP9 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	SpyCas9	Cas9-CFTR-R553X	CFTR-R553X	IDT	Show Experiments (1) Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells
Human	SauCas9	DMD low gRNA-1	One of two low-off target gRNAs delivred by dual gRNA AAV vector pAAV[2gRNA]-mCherry-U6>{SagRNA#1*}:{SagRNA#2}	VectorBuilder	Show Experiments (1) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids.
Human	SauCas9	DMD low gRNA-2	One of two low-off target gRNAs delivred by dual gRNA AAV vector AAV-gRNA	VectorBuilder	Show Experiments (2) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids. Evaluation of DNA damage, cellular toxicity and inflammatory markers following saCas9 and gRNAs delivery by AAV2 in kidney organoids.
Human	SpyCas9	FAS_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	FAS_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	FAS_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	FAS_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	FAS_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Mouse	SauCas9	L1-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (3) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
Mouse	SauCas9	L1-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	L2-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (2) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
Mouse	SauCas9	L2-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	L3-modifed	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	L3-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Human	SpyCas9	LAG3_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_09	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	LAG3_site_10	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	McCray_CFTR_Cas9_Guide1	Targets endogenous human locus	IDT	Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
Human	AsCas12a	NKG2A	gRNA targeting human NKG2A exon 3	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells.
Human		NT-sgRNA	Non targeting guide RNA		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SpyCas9	PDCD1_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_09	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_10	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_11	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_12	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_13	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_14	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_15	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PDCD1_site_16	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN2_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN2_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN2_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_06	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_07	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_08	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	PTPN6_site_09	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Mouse	SpyCas9	Pcsk9 Exon 1 splice domain	Pcsk9 Exon 1 splice domain	Synthego	Show Experiments (2) Pcsk9 adenine base editor efficiency in liver and nonliver tissue Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver
Mouse	SauCas9	R1-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	R1-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	R2-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (2) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	R2-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SpyCas9	R26-1		IDT	Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
Mouse	SpyCas9	R26-2		IDT	Show Experiments (3) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR-2) Mouse Model via Germline Editing
Mouse	SpyCas9	R26-3		IDT	Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
Mouse	SpyCas9	R26-52		IDT	Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR-2) Mouse Model via Germline Editing
Mouse	SpyCas9	R26-59		IDT	Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
Mouse	SpyCas9	R26-69		IDT	Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
Mouse	SpyCas9	STS118 (TLR-MCV1a; Sp_t2-PS:Sp_c20_TLR_MCV1a)	Targets traffic light reporter transgene, CY3 labeled	In house production	Show Experiments (1) Delivery of RNP containing chemically modified crRNA C20 with chemically modified tracrRNA T2-PS to determine the RNP distribution in TLR-MCV mouse brain
Human	SpyCas9	STS118 (TLR-MCV1a; Sp_t2:Sp_c20_TLR_MCV1a)	Targets traffic light reporter transgene	In house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
Human	SpyCas9	STS119 (TLR-MCV1b; Sp_t2:Sp_c20_TLR_MCV1b)	Targets traffic light reporter transgene	In house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
Human	SpyCas9	STS120 (TLR1; Sp_t2:Sp_c20_TLR1)	Targets traffic light reporter transgene	In house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR1 reporter in human cells
Mouse	SpyCas9	STS134 (PCSK9b; Sp_t2:Sp_c20_PCSK9b)	Targets endogenous mouse locus	In house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
Mouse	SpyCas9	STS135 (PCSK9c; Sp_t2:Sp_c20_PCSK9c)	Targets endogenous mouse locus	In house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
Mouse	SpyCas9	STS159 (mTmG; Sp_t2-PS:Sp_c0_mTmG)	This sgRNA targets the mTmG transgene	In house production	Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
Mouse	SpyCas9	STS159 (mTmG; Sp_t2-PS:Sp_c20_mTmG)	This sgRNA targets the mTmG transgene	In house production	Show Experiments (1) Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
Mouse	SpyCas9	STS159 (mTmG; Sp_t2:Sp_c0_mTmG)	This sgRNA targets the mTmG transgene	In house production	Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
Mouse	SpyCas9	STS159 (mTmG; Sp_t2:Sp_c20_mTmG)	This sgRNA targets the mTmG transgene	In house production	Show Experiments (4) Testing newly chemically modified crRNA and tracrRNA in mTmG mouse embryonic fibroblasts Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center Independent validation of Sontheimer delivery platform using heavily modified guide RNAs complexed with Cas9 proteins to deliver CRISPR/Cas9 to mouse brain
Mouse	SpyCas9	STS204 (DNMT1; Sp_t2:Sp_c20_Dnmt1)	For endogenous locus	In house production	Show Experiments (2) Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center Independent validation of Sontheimer delivery platform using heavily modified guide RNAs complexed with Cas9 proteins to deliver CRISPR/Cas9 to mouse brain
Mouse	SpyCas9	STS204 (DNMT1; Sp_t41:Sp_c20_Dnmt1)	Targets endogenous mouse locus	In house production	Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
Mouse	SpyCas9	STS205 (BACE1; Sp_t41:Sp_c20_Bace1)	Targets endogenous mouse locus	In house production	Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
Mouse	SpyCas9	STS96 (PCSK9a; Sp_t2:Sp_c20_PCSK9a)	Targets endogenous mouse locus	In house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
Mouse	SauCas9	SaC9-g1			Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
Mouse	SauCas9	SaC9-g2			Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
Mouse	SauCas9	SaC9-g3			Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
Mouse	SauCas9	SaLoxP1-modified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	SaLoxP1-unmodified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	SaLoxP2-modified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	SaLoxP2-unmodified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9	Sa_Ai9_L	This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016)		Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Mouse	SauCas9	Sa_Ai9_R	This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016)		Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Human	CasΦ-1	SapI-GG stuffer (CasΦ-1)	Non-targeting guide RNA targeting compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2	SapI-GG stuffer (CasΦ-2)	Non-targeting guide RNA targeting compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3	SapI-GG stuffer (CasΦ-3)	Non-targeting guide RNA targeting compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	SgaCas9	SgaCas9-sgRNA1	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SgaCas9	SgaCas9-sgRNA2	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SinCas9	SinCas9-sgRNA1	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SinCas9	SinCas9-sgRNA2	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SpaCas9	SpaCas9-sgRNA1	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SpaCas9	SpaCas9-sgRNA2	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Mouse	SpyCas9	SpyCas9 g-loxP2_C9	This sgRNA targets the mTmG transgene	IDT	Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Human	SpyCas9	SpyCas9-sgRNA1	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SubCas9	SubCas9-sgRNA1	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SubCas9	SubCas9-sgRNA2	Guide RNA targeting the human HBE promoter		Show Experiments (1) Genome editing activity of four Streptococcus Cas9s by gRNA targeting the HBE promoter in HEK293T cells.
Human	SpyCas9	TRAC_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	TRAC_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	TRAC_site_03	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	TRAC_site_04	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	TRAC_site_05	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	TRBC1_site_01	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	TRBC1_site_02	Targets endogenous human locus	Lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9	g-11_C9	sgRNA targeting CFTR exon 11	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Human	AsCas12a	g-38330_C12a	gRNA targeting HPRT locus	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Human	AsCas12a	g-45_C12a	gRNA targeting CFTR inton-22-23	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Mouse	SpyCas9	g-loxP2_C9	This sgRNA targets the Ai9 and related transgenes	IDT	Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
Mouse	AsCas12a	g-loxPbot_C12a	This sgRNA targets the Ai9 and related transgenes at two sites	IDT	Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
Rhesus macaque	SpyCas9	gRNA #8		IDT	Show Experiments (2) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
Mouse	SpyCas9	sg298	This sgRNA targets the Ai9 and related transgenes at multiple sites. 2'-O-Methyl at 3 first and last bases, 3' phosphorothioate bonds between first 3 and last 2 bases	Synthego	Show Experiments (4) Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
Mouse	SpyCas9	sg298	This sgRNA targets the Ai9 and related transgenes at multiple sites	Synthego	Show Experiments (3) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Podocyte-specific gene editing in human kidney organoids
	SpyCas9	sgAi9L	This sgRNA targets the Ai9 and related transgenes	IDT
Human Mouse	SpyCas9	sgAi9L	This sgRNA targets the Ai9 and related transgenes	IDT	Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells
Human Mouse	SpyCas9	sgAi9R	This sgRNA targets the Ai9 and related transgenes	IDT	Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells

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